Electron-dense deposits following injection of Gold Sodium Thiomalate and Thiomalic acid

نویسندگان
چکیده

برای دانلود باید عضویت طلایی داشته باشید

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

Gold sodium thiomalate activates latent human leukocyte collagenase.

Gold sodium thiomalate, a drug used widely in the therapy of rheumatoid arthritis, was found to be an activator of latent human polymorphonuclear leukocyte collagenase. The activation was demonstrated by two distinct and independent collagenase assays: by recording with a spectrophotometer at 227 nm the enzyme-induced increase in ultraviolet difference absorbance of native type I collagen conne...

متن کامل

A light and electron microscopic study of the distribution of gold sodium thiomalate in the rheumatoid synovial membranes.

The synovial membranes from 16 rheumatoid patients treated with intramuscular injections of gold sodium thiomalate were observed by light and electron microscopy with special reference to the distribution of gold particles in the tissue. 1) Light microscopic study revealed that the gold demonstrated as cytoplasmic granules by OKAMOTO’S histochemical method were contained in the synovial lining ...

متن کامل

complications of gold sodium thiomalate therapy in rheumatoid arthritis

to determine the complications of gold sodium thiomalate therapy in rheumatoid arthritis (ra), 32 patients with active ra (27 female, 5 male) treated for a mean period of 28 ? 14 weeks were studied. from these patients, 62.5 (46-79) percent showed at least one drug reaction. pruritus was the most common complication occurred in 59 (42-76) percents, and was accompanied by skin rush in 37 (15-57)...

متن کامل

ADVERSE REACTIONS OF GOLD SODIUM THIOMALATE IN RHEUMATOID ARTHRI TIS PATIENTS IN SOUTHERN IRAN

To confirm the side-effects of gold sodium thiomalate (GSTM), we carried out a retrospective study examining 102 consecutive patients with rheumatoid arthritis attending the Rheumatology Unit of Hafez Hospital, Shiraz, Iran, in whom GSTM was initiated between 1983-1989. Only patients with classical or definite RA (ARA criteria) we(e included in this study. Patients were categorized as havi...

متن کامل

The effect of gold sodium thiomalate in adult Swiss/A2G mice infected with togaviruses and flaviviruses.

Treatment of adult mice with gold sodium thiomalate made the normally non-lethal Semliki Forest virus and Sindbis virus infections lethal and increased the virulence of Langat and West Nile viruses. These changes were associated with an enhanced virus invasion of the brain. Depression of the humoral antibody response was not observed.

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

ژورنال

عنوان ژورنال: Arthritis & Rheumatism

سال: 1968

ISSN: 0004-3591,1529-0131

DOI: 10.1002/art.1780110309